Sandeep Tyagi Selected Research

Pyrazinamide

1/2017	Bactericidal and Sterilizing Activity of a Novel Regimen with Bedaquiline, Pretomanid, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis.
5/2014	Revisiting Anti-tuberculosis Activity of Pyrazinamide in Mice.
9/2013	Assessment of clofazimine activity in a second-line regimen for tuberculosis in mice.
7/2013	Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis.
11/2012	Activity of 5-chloro-pyrazinamide in mice infected with Mycobacterium tuberculosis or Mycobacterium bovis.
9/2012	Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide.
7/2011	Effectiveness of tuberculosis chemotherapy correlates with resistance to Mycobacterium tuberculosis infection in animal models.
10/2009	Paradoxical effect of isoniazid on the activity of rifampin-pyrazinamide combination in a mouse model of tuberculosis.
10/2008	Enhanced bactericidal activity of rifampin and/or pyrazinamide when combined with PA-824 in a murine model of tuberculosis.
4/2008	Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis.

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Sandeep Tyagi Research Topics

Disease

38	Tuberculosis (Tuberculoses) 01/2022 - 06/2002
21	Infections 01/2020 - 06/2002
8	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2018 - 06/2005
6	Buruli Ulcer 01/2020 - 01/2013
3	Body Weight (Weight, Body) 01/2019 - 06/2002
2	Latent Tuberculosis 01/2019 - 12/2005
2	Granuloma 09/2013 - 07/2011
1	Persistent Infection 01/2021
1	Vaccinia 01/2018
1	Leprosy (Hansen's Disease) 01/2015
1	Hearing Loss (Hearing Impairment) 01/2015
1	Neglected Diseases 01/2014
1	Hypertension (High Blood Pressure) 07/2012
1	Dyslipidemias (Dyslipidemia) 10/2011
1	Inflammation (Inflammations) 10/2011
1	Lung Neoplasms (Lung Cancer) 10/2011
1	Obesity 10/2011
1	Pain (Aches) 10/2011
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2011
1	Necrosis 02/2005
1	Hypersensitivity (Allergy) 03/2004
1	Drug-Related Side Effects and Adverse Reactions 06/2002
1	Weight Gain 06/2002

Drug/Important Bio-Agent (IBA)

16	Pharmaceutical PreparationsIBA 01/2022 - 06/2005
13	Pyrazinamide FDA LinkGeneric 01/2017 - 02/2004
13	Moxifloxacin (Avelox)FDA Link 01/2017 - 06/2002
11	Rifampin (Rifampicin)FDA LinkGeneric 01/2020 - 02/2004
10	AerosolsIBA 01/2019 - 03/2004
9	Isoniazid (Ftivazide)FDA LinkGeneric 01/2019 - 06/2002
8	pretomanidIBA 01/2021 - 06/2005
6	rifapentine (Priftin)FDA Link 01/2019 - 12/2005
6	Clofazimine (Lamprene)FDA Link 01/2019 - 09/2013
5	bedaquiline (R207910)IBA 01/2019 - 01/2015
4	Drug CombinationsIBA 01/2022 - 10/2008
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 07/2011
3	VaccinesIBA 01/2020 - 03/2004
3	RifamycinsIBA 01/2019 - 07/2006
3	Streptomycin (Streptomycin Sulfate)FDA Link 06/2015 - 01/2013
3	Ethambutol (Myambutol)FDA LinkGeneric 09/2013 - 12/2005
2	Antitubercular AgentsIBA 01/2022 - 01/2020
2	Linezolid (Zyvox)FDA Link 01/2021 - 08/2009
2	telacebecIBA 01/2020 - 01/2019
2	Oxazolidinones (2 Oxazolidone)IBA 01/2016 - 08/2009
2	Verapamil (Calan)FDA LinkGeneric 01/2015 - 09/2013
2	Amikacin (A.M.K)FDA LinkGeneric 09/2013 - 03/2013
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2005 - 03/2004
2	Transcription Factors (Transcription Factor)IBA 04/2004 - 06/2002
1	Delayed-Action PreparationsIBA 01/2019
1	Oxidoreductases (Dehydrogenase)IBA 01/2019
1	AntigensIBA 01/2018
1	BCG Vaccine FDA Link 01/2018
1	Adenosine Triphosphate (ATP)IBA 01/2016
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 06/2015
1	Clarithromycin (Biaxin)FDA LinkGeneric 04/2015
1	ProdrugsIBA 05/2014
1	EnzymesIBA 05/2014
1	AcidsIBA 01/2014
1	Levofloxacin (Levaquin)FDA Link 07/2013
1	FluoroquinolonesIBA 07/2013
1	mycolactoneIBA 01/2013
1	trichostatin A (A 300)IBA 11/2012
1	Acetates (Acetic Acid Esters)FDA Link 07/2012
1	Glutathione (Reduced Glutathione)IBA 07/2012
1	Desoxycorticosterone Acetate (DOCA)FDA Link 07/2012
1	NitratesIBA 07/2012
1	NitritesIBA 07/2012
1	2,4-thiazolidinedione (thiazolidinedione)IBA 07/2012
1	Acetylcholine (Acetylcholine Chloride)FDA Link 07/2012
1	Phosphatidylinositols (Phosphatidylinositol)IBA 07/2012
1	SaltsIBA 07/2012
1	Desoxycorticosterone (Deoxycorticosterone)IBA 07/2012
1	Losartan (Cozaar)FDA LinkGeneric 07/2012
1	Atorvastatin (Lipitor)FDA Link 07/2012
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2011
1	NitroimidazolesIBA 01/2011
1	PNU-100480IBA 08/2009
1	CytokinesIBA 11/2008
1	DNA (Deoxyribonucleic Acid)IBA 12/2005
1	DNA VaccinesIBA 12/2005
1	Ethionamide (Trecator-SC)FDA Link 12/2005
1	Sigma FactorIBA 02/2005
1	HoloenzymesIBA 02/2005
1	Tuberculin (PPD)IBA 03/2004
1	LipopolysaccharidesIBA 03/2004
1	Virulence Factors (Pathogenicity Factors)IBA 06/2002
1	ThioredoxinsIBA 06/2002

Therapy/Procedure

8	Therapeutics 01/2019 - 06/2002
6	Duration of Therapy 01/2022 - 02/2004
5	Drug Therapy (Chemotherapy) 01/2015 - 02/2004
1	Injections 01/2019
1	Intramuscular Injections 01/2015
1	Skin Transplantation (Skin Grafting) 01/2015
1	Aftercare (After-Treatment) 01/2013
1	Subcutaneous Injections 07/2012
1	Combination Drug Therapy (Combination Chemotherapy) 08/2006